Framework Selection Matters. The most effective AI governance programs integrate multiple frameworks: NIST AI RMF for lifecycle risk management, ISO 42001 for certifiable management systems, sector-specific regulations for compliance, and foundational security controls for infrastructure protection.
AI-Specific Frameworks
NIST AI RMF
U.S. StandardThe foundational U.S. standard for AI risk management. Four core functions—GOVERN, MAP, MEASURE, MANAGE—structure AI governance across the lifecycle.
ISO/IEC 42001
International StandardThe world's first certifiable AI management system standard. 38 controls for demonstrable AI governance through independent audit.
Security and Compliance Frameworks
NIST SP 800-53
Security ControlsThe definitive catalog of security and privacy controls. 20 control families providing foundational infrastructure for AI systems.
FedRAMP
Cloud AuthorizationFederal cloud authorization program. Required for AI services sold to U.S. government agencies. Major 20x overhaul in 2025.
Asset and Infrastructure Frameworks
Framework Integration
Organizations in regulated industries typically need multiple frameworks working together:
Financial Services: NIST AI RMF + SR 11-7 + NIST 800-53
Insurance: NIST AI RMF + NAIC Model Bulletin + Colorado SB 21-169
Utilities: ISO 55000 + NIST AI RMF + NERC CIP
Federal Contractors: FedRAMP + NIST 800-53 + NIST AI RMF
EU Market Access: ISO 42001 + EU AI Act